You guys might have heared about the game Hatred. It uses the Unreal Engine 4.
Skip to 5 minutes in.
I just watched this video of it and it made me think of Jagged Alliance. I don't mean the setting and killing of civilian. I mean the engine, the isometric view, the physics and the destructable enviroment.
Some how it clicked.
I think there's a thing on the engine made specifically for doing that. Can't link it because I'm too sleepy to go search. I just remember a sort of basic tech demo video in a very plain environment (clean, white. destructible stuff maybe).